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1

201. Cerebrospinal Fluid Drainage and Pressure Monitoring After Acute Human Spinal Cord Injury

Brian Kwon, Lise Belanger, Donna Chan, Arlene Bernardo, Gerard Slobogean, Michael Boyd, Scott Paquette, Hamed Umedaly, Mitch Giffin, John Street, Charles Fisher, Armin Curt, Marcel Dvorak

Journal:

The Spine Journal

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

2

Factors affecting neurological outcome in traumatic conus medullaris and cauda equina injuries

Kingwell, Stephen P., Curt, Armin, Dvorak, Marcel F.

Journal:

Neurosurgical FOCUS

Year:

2008

File:

PDF, 1.38 MB

2008

3

The Synthesis of Streptogramin Antibiotics: (−)-Griseoviridin and Its C-8 Epimer

Curt A. Dvorak, William D. Schmitz, Daniel J. Poon, David C. Pryde, Jon P. Lawson, Richard A. Amos, Albert I. Meyers

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

4

The Synthesis of Streptogramin Antibiotics: (−)-Griseoviridin and Its C-8 Epimer

Curt A. Dvorak, William D. Schmitz, Daniel J. Poon, David C. Pryde, Jon P. Lawson, Richard A. Amos, Albert I. Meyers

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

5

ChemInform Abstract: The Synthesis of Streptogramin Antibiotics: (-)-Griseoviridin and Its C-8 Epimer.

Curt A. Dvorak, William D. Schmitz, Daniel J. Poon, David C. Pryde, Jon P. Lawson, Richard A. Amos, Albert I. Meyers

Journal:

Year:

2000

File:

PDF, 27 KB

2000

6

ChemInform Abstract: An Asymmetric Approach to Spirocyclic Systems: A Formal Synthesis of Zizaene.

Robert C. Hughes, Curt A. Dvorak, A. I. Meyers

Journal:

Year:

2001

File:

PDF, 37 KB

2001

7

Novel Substituted 4-Phenyl-[1,3]dioxanes: Potent and Selective Orexin Receptor 2 (OX2R) Antagonists.

Laura C. McAtee, Steven W. Sutton, Dale A. Rudolph, Xiaobing Li, Leah E. Aluisio, Victor K. Phuong, Curt A. Dvorak, Timothy W. Lovenberg, Nicholas I. Carruthers, Todd K. Jones

Journal:

Year:

2004

File:

PDF, 19 KB

2004

8

Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids.

Curt A. Dvorak, Dale A. Rudolph, Sandy Ma, Nicholas I. Carruthers

Journal:

Year:

2005

File:

PDF, 26 KB

2005

9

Novel imidazole-based histamine H3 antagonists

Jill A. Jablonowski, Kiev S. Ly, Michael Bogenstaetter, Curt A. Dvorak, Jamin D. Boggs, Lisa K. Dvorak, Brian Lord, Kirsten L. Miller, Curt Mazur, Sandy J. Wilson, Timothy W. Lovenberg, Nicholas I. Ca

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

10

Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX2R) antagonists

Laura C McAtee, Steven W Sutton, Dale A Rudolph, Xiaobing Li, Leah E Aluisio, Victor K Phuong, Curt A Dvorak, Timothy W Lovenberg, Nicholas I Carruthers, Todd K Jones

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004

11

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists

Brock T. Shireman, Curt A. Dvorak, Dale A. Rudolph, Pascal Bonaventure, Diane Nepomuceno, Lisa Dvorak, Kirsten L. Miller, Timothy W. Lovenberg, Nicholas I. Carruthers

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

12

Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]

Brock T. Shireman, Curt A. Dvorak, Dale A. Rudolph, Pascal Bonaventure, Diane Nepomuceno, Lisa Dvorak, Kirsten L. Miller, Timothy W. Lovenberg, Nicholas I. Carruthers

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 111 KB

english, 2008

13

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT7 antagonists

Dale A. Rudolph, Curt A. Dvorak, Lisa Dvorak, Diane Nepomuceno, Pascal Bonaventure, Timothy W. Lovenberg, Nicholas I. Carruthers

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 325 KB

english, 2011

14

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists

Devin M. Swanson, Chandra R. Shah, Brian Lord, Kirsten Morton, Lisa K. Dvorak, Curt Mazur, Richard Apodaca, Wei Xiao, Jamin D. Boggs, Mark Feinstein, Sandy J. Wilson, Ann J. Barbier, Pascal Bonaventur

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 542 KB

english, 2009

15

Diamine-based human histamine H3 receptor antagonists: (4-Aminobutyn-1-yl)benzylamines

Curt A. Dvorak, Richard Apodaca, Wei Xiao, Jill A. Jablonowski, Pascal Bonaventure, Christine Dugovic, Jonathan Shelton, Brian Lord, Kirsten Miller, Lisa K. Dvorak, Timothy W. Lovenberg, Nicholas I. C

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 973 KB

english, 2009

16

Catalysis of benzoin condensation by conformationally-restricted chiral bicyclic thiazolium salts

Curt A Dvorak, Viresh H Rawal

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 237 KB

english, 1998

17

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor

Devin M. Swanson, Victoria D. Wong, Jill A. Jablonowski, Chandra Shah, Dale A. Rudolph, Curt A. Dvorak, Mark Seierstad, Lisa K. Dvorak, Kirsten Morton, Diane Nepomuceno, John R. Atack, Pascal Bonavent

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.73 MB

english, 2011

18

Pharmacological characterization of JNJ-28583867, a histamine H3 receptor antagonist and serotonin reuptake inhibitor

Ann J. Barbier, Leah Aluisio, Brian Lord, Ying Qu, Sandy J. Wilson, Jamin D. Boggs, Pascal Bonaventure, Kirsten Miller, Ian Fraser, Lisa Dvorak, Cindy Pudiak, Christine Dugovic, Jonathan Shelton, Curt

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 568 KB

english, 2007

19

Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists

Da-Thao Tran, Pascal Bonaventure, Michael Hack, Taraneh Mirzadegan, Curt Dvorak, Michael Letavic, Nicholas Carruthers, Timothy Lovenberg, Steven W. Sutton

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 861 KB

english, 2011

20

An Asymmetric Approach to Spirocylic Systems: A Formal Synthesis of Zizaene†

Hughes, Robert C., Dvorak, Curt A., Meyers, A. I.

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

21

Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids

Dvorak, Curt A., Rudolph, Dale A., Ma, Sandy, Carruthers, Nicholas I.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 138 KB

english, 2005

22

Myelin water and T2 relaxation measurements in the healthy cervical spinal cord at 3.0T: Repeatability and changes with age

Erin L. MacMillan, Burkhard Mädler, Nicole Fichtner, Marcel F. Dvorak, David K.B. Li, Armin Curt, Alex L. MacKay

Journal:

Year:

2011

Language:

english

File:

PDF, 806 KB

english, 2011

23

Preparation and Biological Evaluation of Indole, Benzimidazole, and Thienopyrrole Piperazine Carboxamides: Potent Human Histamine H 4 Antagonists

Venable, Jennifer D., Cai, Hui, Chai, Wenying, Dvorak, Curt A., Grice, Cheryl A., Jablonowski, Jill A., Shah, Chandra R., Kwok, Annette K., Ly, Kiev S., Pio, Barbara, Wei, Jianmei, Desai, Pragnya J.,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

24

The First Potent and Selective Non-Imidazole Human Histamine H 4 Receptor Antagonists

Jablonowski, Jill A., Grice, Cheryl A., Chai, Wenying, Dvorak, Curt A., Venable, Jennifer D., Kwok, Annette K., Ly, Kiev S., Wei, Jianmei, Baker, Sherry M., Desai, Pragnya J., Jiang, Wen, Wilson, Sand

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

25

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects

Dvorak, Curt A., Liu, Changlu, Shelton, Jonathan, Kuei, Chester, Sutton, Steven W., Lovenberg, Timothy W., Carruthers, Nicholas I.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

26

A New Class of Diamine-Based Human Histamine H 3 Receptor Antagonists: 4-(Aminoalkoxy)benzylamines

Apodaca, Richard, Dvorak, Curt A., Xiao, Wei, Barbier, Ann J., Boggs, Jamin D., Wilson, Sandy J., Lovenberg, Timothy W., Carruthers, Nicholas I.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

27

4-Phenoxypiperidines: Potent, Conformationally Restricted, Non-Imidazole Histamine H 3 Antagonists

Dvorak, Curt A., Apodaca, Richard, Barbier, Ann J., Berridge, Craig W., Wilson, Sandy J., Boggs, Jamin D., Xiao, Wei, Lovenberg, Timothy W., Carruthers, Nicholas I.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 252 KB

english, 2005

28

Complexation of a Singlet Carbene by a Fluoroalkane. Modification of 1:CHCO2Et Selectivity in Perfluorohexane Solution and ab Initio Calculations

Swanson, Judith M., Dvorak, Curt A., DeLuca, JoAnn P., Standard, Jean M.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 855 KB

english, 1994

29

Rapid Synthesis of Di- and Triquinanes by Direct Reductive Fragmentation of Paterno−Büchi-Derived Oxetanes

Dvorak, Curt A., Dufour, Claire, Iwasa, Seiji, Rawal, Viresh H.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 39 KB

english, 1998

30

Stereodirecting effect of a substrate methoxy substituent on the addition of singlet methylene to a double bond

Young, Terry A., O'Rourke, Colleen, Gray, Nathan B., Lewis, Brian D., Dvorak, Curt A., Kuen, Kan Shuh, DeLuca, JoAnn P.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 610 KB

english, 1993

31

Synthesis of the naturally occurring [3.3.3]propellane (±)-modhephene featuring a photocycloaddition–reductive fragmentation diquinane construction

Dvorak, Curt A., Rawal, Viresh H.

Journal:

Chemical Communications

Year:

1997

Language:

english

File:

PDF, 51 KB

english, 1997

32

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor

Dvorak, Curt A., Coate, Heather, Nepomuceno, Diane, Wennerholm, Michelle, Kuei, Chester, Lord, Brian, Woody, David, Bonaventure, Pascal, Liu, Changlu, Lovenberg, Timothy, Carruthers, Nicholas I.

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 294 KB

english, 2015

33

Factors affecting neurological outcome in traumatic conus medullaris and cauda equina injuries

Kingwell, Stephen P., Curt, Armin, Dvorak, Marcel F.

Journal:

Neurosurgical FOCUS

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

34

Allyl-assisted, Cu(I) Catalyzed Azide-alkyne Cycloaddition/Allylation Reaction: One-pot Assembly of the [1,2,3]Triazolo-4,5,6,7-tetrahydro-pyridine Core Structure

Deng, Xiaohu, Liang, Jimmy, Allison, Brett B., Dvorak, Curt, McAllister, Heather, Savall, Brad M., Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 540 KB

english, 2015

35

Encyclopedia of Reagents for Organic Synthesis || 2,4-Dichloropyrimidine

Dvorak, Curt A.

Year:

2001

Language:

english

File:

PDF, 54 KB

english, 2001

36

Thoracic Disc Herniation in a Patient With Tethered Cord and Lumbar Syringomyelia and Diastematomyelia

Kramer, John L. K., Dvorak, Marcel, Curt, Armin

Journal:

Year:

2009

Language:

english

File:

PDF, 502 KB

english, 2009

37

ChemInform Abstract: Allyl-Assisted, Cu(I)-Catalyzed Azide-Alkyne Cycloaddition/Allylation Reaction: Assembly of the [1,2,3]Triazolo-4,5,6,7-tetrahydropyridine Core Structure.

Deng, Xiaohu, Liang, Jimmy, Allison, Brett B., Dvorak, Curt, McAllister, Heather, Savall, Brad M., Mani, Neelakandha S.

Journal:

Year:

2016

File:

PDF, 26 KB

2016

38

Assessing structure and function of myelin in cervical spondylotic myelopathy

Liu, Hanwen, MacMillian, Erin L., Jutzeler, Catherine R., Ljungberg, Emil, MacKay, Alex L., Kolind, Shannon H., Mädler, Burkhard, Li, David K.B., Dvorak, Marcel F., Curt, Armin, Laule, Cornelia, Krame

Journal:

Year:

2017

Language:

english

File:

PDF, 792 KB

english, 2017

39

A dipolar cycloaddition reaction to access 6-methyl-4,5,6,7-tetrahydro-1 H -[1,2,3]triazolo[4,5- c ]pyridines enables the discovery synthesis and preclinical profiling of a P2X7 antagonist clinical candidate

Chrovian, Christa C, Soyode-Johnson, Akinola, Peterson, Alexander A, Gelin, Christine F., Deng, Xiaohu, Dvorak, Curt A., Carruthers, Nicholas I., Lord, Brian, Fraser, Ian, Aluisio, Leah, Coe, Kevin J,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 797 KB

english, 2017

40

Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity

Shelton, Jonathan, Yun, Sujin, Losee Olson, Susan, Turek, Fred, Bonaventure, Pascal, Dvorak, Curt, Lovenberg, Timothy, Dugovic, Christine

Journal:

Frontiers in Behavioral Neuroscience

Year:

2015

Language:

english

File:

PDF, 831 KB

english, 2015

41

Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro

Nepomuceno, Diane, Kuei, Chester, Dvorak, Curt, Lovenberg, Timothy, Liu, Changlu, Bonaventure, Pascal

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 3.01 MB

english, 2018

42

Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793

PrÃ©ville, Cathy, Bonaventure, Pascal, Koudriakova, Tatiana, Lord, Brian, Nepomuceno, Diane, Rizzolio, Michele, Mani, Neelakandha, Coe, Kevin J., Ndifor, Anthony, Dugovic, Christine, Dvorak, Curt A.,

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 318 KB

2020

43

Putative role of GPR139 on sleep modulation using pharmacological and genetic rodent models

Wang, Lien, Dugovic, Christine, Yun, Sujin, White, Allison, Lord, Brian, Dvorak, Curt, Liu, Changlu, Lovenberg, Timothy, Bonaventure, Pascal

Journal:

European Journal of Pharmacology

Year:

2020

File:

PDF, 2.13 MB

2020

44

Discovery and SAR Studies of 2-Alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 Inhibitors Leading to the Identification of a Clinical Candidate

Dvorak, Curt A., Rudolph, Dale A., Nepomuceno, Diane, Dvorak, Lisa, Lord, Brian, Fraser, Ian, Bonaventure, Pascal, Lovenberg, Timothy, Carruthers, Nicholas I.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 1.15 MB

2020